Sodium Oxybate Improves Excessive Daytime Sleepiness in Narcolepsy
نویسندگان
چکیده
منابع مشابه
Sodium oxybate for excessive daytime sleepiness in Parkinson disease: an open-label polysomnographic study.
BACKGROUND Many patients with Parkinson disease (PD) have excessive daytime sleepiness and numerous nocturnal sleep abnormalities. OBJECTIVE To determine the safety and efficacy of the controlled drug sodium oxybate in a multicenter, open-label, polysomnographic study in subjects with PD and sleep disorders. Design, Setting, and Patients Inclusion required an Epworth Sleepiness Scale (ESS) sc...
متن کاملSodium Oxybate for Narcolepsy
1a. Is sodium oxybate safe and clinically effective in the reduction in number and intensity of cataplexy attack, excessive day-time sleepiness (diurnal naps), nocturnal awakenings, terrifying dream experiences, insomnia, hypnagogic hallucinations, sleep paralysis, and improvement in quality of life in adult patients with narcolepsy and cataplexy compared to no intervention, combined treatment ...
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Excessive daytime sleepiness is one of the most common sleep-related patient symptoms, and it affects an estimated 20 percent of the population. Persons with excessive daytime sleepiness are at risk of motor vehicle and work-related incidents, and have poorer health than comparable adults. The most common causes of excessive daytime sleepiness are sleep deprivation, obstructive sleep apnea, and...
متن کاملPharmacotherapy for excessive daytime sleepiness.
Excessive daytime sleepiness (EDS) has recognized detrimental consequences such as road traffic accidents, impaired psychological functioning and reduced work performance. EDS can result from multiple causes such as sleep deprivation, sleep fragmentation, neurological, psychiatric and circadian rhythm disorders. Treating the underlying cause of EDS remains the mainstay of therapy but in those w...
متن کاملth17 cell related cytokine profiles in narcolepsy and other types of excessive daytime sleepiness
background and objective : narcolepsy is a chronic neurological disorder caused by loss of hypocretin (hcrt) neurons. both genetic and environmental factors play an important role for the development of narcolepsy. the mechanism of hcrt loss in narcolepsy is elusive; however, an autoimmune mediated destruction of hcrt neurons is suspected. the purpose of this study was to assess th17 related cy...
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ژورنال
عنوان ژورنال: Sleep
سال: 2006
ISSN: 1550-9109,0161-8105
DOI: 10.1093/sleep/29.7.939